 Previously I was a postdoctoral fellow at the European Molecular Biology Lab - European Bioinformatics Institute (EMBL-EBI). I am working in the ChEMBL group headed by John Overington and collaborating with the group of Stephen Cusack in Grenoble. My PhD was in the field of of proteochemometric modeling at the Leiden Amsterdam Center for Drug Research. In essence this relatively new technique allows for the creation of advanced structure-activity relations based on ligand information, protein information and mutual dependencies. It can therefore map structure activity relations between a series of compounds and a series of proteins including pair specific interaction data. Proteochemometric modeling can effectively separate chance correlations from real structure activity correlations when using very large datasets. Developing this technique and characterizing its advantages and possible shortcomings is the aim of my work at Medicinal Chemistry. This project is a collaboration between Leiden University and Tibotec BVBA Belgium. Before that I studied Biopharmaceutical Sciences at Leiden University from September 2001 until September 2007. With two major internships. The first one was within the LACDR on a biochemical project. The second one was something completely different on a computational project at Tibotec in Mechelen Belgium. It was here that I discovered the challenging side of computational research. I am always interested in collaborations, you can email me at |
   
  
|
|
