Curriculum Vitae

March 21st 2017

Leiden University

Leiden Academic Centre for Drug Research (LACDR)

Medicinal Chemistry, Einsteinweg 55

2333 CC, Leiden, Telephone: +31 6 19010 038


Keywords: computational chemist, modeling, polypharmacology, big data

scientific presenting, scientific writing, linux administration

Scientific and personal interests

· Predictive polypharmacology, cheminformatics, bioinformatics, text mining, interdisciplinary research, big data, high performance / GPU computing, visualization

· Computer geek (likes tinkering with hardware and networks), ZFS, open fire cooking, likes driving / road tripping

Skill set

· Statistical modeling, big data analysis, visualization & dimensionality reduction, workflow tools, scripting in several languages, structure based modeling, SQL, high performance computing

Scientific Publications

· 36 Articles in peer-reviewed international journals (h-index 18, average impact factor 8, average citations per paper 28), multiple talks and poster presentations at scientific meetings (see

Current Positions

· Assistant Professor (Tenure Track, Drug & Target Discovery Cluster) 10/2016 – Present

o Computational Chemical Biology

· Founder of Getuyg Data Analytics 07/2015 – Present

o Data science and storage consultancy

Previous Positions

· Senior Postdoc Medicinal Chemistry (LACDR) 05/2015 – 09/2016

o Fellowship at Science Faculty (LACDR & LIACS)

· Senior Postdoc ChEMBL group 11/2013 – 05/2015

o EMBL Interdisciplinary POstDoc (EIPOD) fellowship

· Guest Scientist Leiden University (LACDR) 09/2014 – 05/2015

· Guest Scientist University of Cambridge 08/2014 – 08/2014

· Guest Lecturer University of Strathclyde (Glasgow) 12/2013 – 12/2014

· Postdoctoral fellow ChEMBL group 05/2012 – 11/2013

o EMBL Interdisciplinary POstDoc (EIPOD) fellowship

Consultancy work

· CULGI (chemical modeling company, Leiden, Netherlands)

· Stage Pharma (biotech startup, Utrecht, Netherlands)

o Generation of polypharmacological predictive models (aminergic GPCRs)

· Johnson & Johnson Pharmaceuticals (Beerse, Belgium)

o Predictive polypharmacological models in discovery


· Ph.D. in Proteochemometrics (polypharmacology modeling) 11/2007 – 01/2013

Leiden Academic Center for Drug Research (Leiden University, The Netherlands)

o Predictive computational models using ligand and protein similarity simultaneously (Proteochemometrics, Ph.D. position was funded by Janssen Pharmaceutica (Johnson and Johnson Pharmaceuticals)

· M.Sc. Bio-Pharmaceutical Sciences 09/2001 – 09/2007

Leiden University (Leiden, The Netherlands) with the following research projects:

o Characterizing the inhibition of P-Selectin by GA-GWVDV (36 weeks, molecular biology; department of Bio-Pharmaceutics of the LACDR)

o Characterizing HIV-1 Reverse Transcriptase Non-Nucleoside Reverse Transcriptase Inhibitor Resistance (24 weeks, chem-informatics, department of Chem-informatics and Modeling of Tibotec / Janssen Pharmaceutica Belgium)

Supervision and Teaching

· Chem and Bioinformatics in Computational biomedical and drug research.

· Portfolio assignment in Design and Synthesis.

· Cheminformatics in Minor ‘Modern Drug Discovery’.

· Designed practical course “Computational Drug Design”, 10-day course on the fundamentals of computational drug design (given twice to 20 students).

· Supervision of 2 Postdocs, 2 PhD Student, > 10 M.Sc. students, and > 10 B.Sc. students

Reviewing Activities

· Ad hoc referee for the following peer reviewed journals: ACS Medicinal Chemistry Letters. Bioinformatics, Journal of Structural Biology, Journal of Medicinal Chemistry, Journal of Chemical Information & Modeling, Journal of Cheminformatics, Molecular Informatics, Nature Methods

· 2015 EIPOD interviews (external expert)

Management & organization

• Served 1 year as postdoc representative at EBI. Duties included liaising between postdocs and EBI or EMBL faculty, feedback with regard to the training program, organizing symposia and lunch-meetings, inviting external speakers.

• Member of organizing committee for EMBL postdoc retreat. Bi-annual 3 day event, 2 days scientific program and 1 afternoon of social program. Attended by approximately 80 international postdocs from EMBL outstations in Heidelberg, Grenoble, Hamburg, Hinxton, and Monterotondo. Additionally, the committee hosted a number of external speakers from academia, industry, and academic publishing.

• Founder of Camball annual classic rally (2012 – Present)

• Crew at checkpoint Amsterdam for Gumball 3000 rally (2010 – 2015)

• Served a year on the Science Club committee, in charge of the faculty café that provides a venue for symposia, discussion, and hosting of weekly science faculty drinks on Thursday

• Served a year as president of L.P.S.V. ,,Aesculapius” , student association [1]

[1]Was a member of various committees including: Dies Natalis Committee, Freshmen Weekend Committee, Yearbook Committee and Internet Committee during membership of the L.P.S.V. „Aesculapius”